Studies related to Urea and Cocoa Extract

Sustained Benefits In Vascular Function Through Flavanol-containing Cocoa In Medicated Diabetic Patients A Double-masked, Randomized, Controlled Trial

Effect None
Trial Design Double blind
Trial Length 2-4 Weeks
Number of Subjects 41
Sex Both Genders
Age Range 45-64
Body Types Obese
Notes for this study:
In type II diabetics on medication, supplementation of dark chocolate (75, 371, or 963mg of flavanols; highest dose having 203mg epicatechin) was able to acutely increased blood flow in a dose-dependent manner. There were no changes in heart rate, blood pressure, or glycemic control. HbA1c did decrease, but evenly so in both groups.

30 days of ingestion at the highest dose (963mg, three doses of 321mg) improved blood flow 30% under basal conditions, while each dose acutely improved blood flow slightly more (but then normalized to 30% during the supplementation period).