Studies related to Mitochondrial Protection and Cocoa Extract

Alterations In Skeletal Muscle Indicators Of Mitochondrial Structure And Biogenesis In Patients With Type 2 Diabetes And Heart Failure: Effects Of Epicatechin Rich Cocoa

Effect Increase
Trial Design Non-controlled trial
Trial Length 1-6 months
Number of Subjects 5
Sex Both Genders
Age Range 65+
Body Types Obese, Overweight
Notes for this study:
A preliminary study of five people who had both type II diabetes and heart failure (stage II/III) given (-)-epicatechin in a beverage at the dose of 100mg daily for three months noted benefits to mitochondrial function in skeletal muscle as assessed by biomarkers of mitochondrial function and their cristae.

Patients at baseline had impaired mitochondrial function and deteriorating cristae.
Funding issues for this study:
Study funded by Hershey