| Effect | Increase |
| Trial Design | Non-controlled trial |
| Trial Length | 1-6 months |
| Number of Subjects | 5 |
| Sex | Both Genders |
| Age Range | 65+ |
| Body Types | Obese, Overweight |
A preliminary study of five people who had both type II diabetes and heart failure (stage II/III) given (-)-epicatechin in a beverage at the dose of 100mg daily for three months noted benefits to mitochondrial function in skeletal muscle as assessed by biomarkers of mitochondrial function and their cristae.Funding issues for this study:
Patients at baseline had impaired mitochondrial function and deteriorating cristae.
Study funded by Hershey
