| Effect | None |
| Trial Design | Non-controlled trial |
| Trial Length | 2-4 Weeks |
| Number of Subjects | 70 |
| Sex | Male |
| Age Range | 45-64, 65+ |
| Body Types | Overweight |
In a comparative study between a normal 58% cocoa product at 70g (259mg flavanols and 97mg (-)-epicatechin) and an enhanced product (1047mg flavanols with 349mg (-)-epicatechin) over four weeks both products seemed to perform equally against each other; there was no flavanol-free product to use as reference.
Relative to baseline values, both groups experiences a decrease in some cellular adhesion factors (leukocytes and neutrophils tested) and improved blood flow as assessed by FMD; the inflammatory response from an acute high fat test meal was attenuated in both groups.
A minor increase in blood glucose and free fatty acids seen in both groups was attributed to the caloric components of the test chocolate.
