Studies related to Interleukin 1-beta and Cocoa Extract

Dark Chocolate Consumption Improves Leukocyte Adhesion Factors And Vascular Function In Overweight Men

Effect None
Trial Design Non-controlled trial
Trial Length 2-4 Weeks
Number of Subjects 70
Sex Male
Age Range 45-64, 65+
Body Types Overweight
Notes for this study:
In a comparative study between a normal 58% cocoa product at 70g (259mg flavanols and 97mg (-)-epicatechin) and an enhanced product (1047mg flavanols with 349mg (-)-epicatechin) over four weeks both products seemed to perform equally against each other; there was no flavanol-free product to use as reference.

Relative to baseline values, both groups experiences a decrease in some cellular adhesion factors (leukocytes and neutrophils tested) and improved blood flow as assessed by FMD; the inflammatory response from an acute high fat test meal was attenuated in both groups.

A minor increase in blood glucose and free fatty acids seen in both groups was attributed to the caloric components of the test chocolate.

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