Studies related to Homocysteine and Cocoa Extract

Blood Pressure Is Reduced And Insulin Sensitivity Increased In Glucose-intolerant, Hypertensive Subjects After 15 Days Of Consuming High-polyphenol Dark Chocolate

Effect None
Trial Design Double blind
Trial Length 1-2 Weeks
Number of Subjects 19
Sex Both Genders
Age Range 30-44, 45-64
Body Types Overweight
Notes for this study:
In essential hypertensives with impaired glucose tolerance given 50g of dark chocolate (1009mg phenols, 111mg epicatechin) twice a day for 15 days improved blood pressure (systolic, diastolic, and ambulatory) and improved insulin sensitivity as assessed by QUICKI and HOMA-IR; an improvement in beta-cell function appeared to also exist alongside modest improvements in cholesterol.

Blood flow (FMD) improved, but other serum parameters related to inflammation and methylation did not.
Funding issues for this study:
Napoleone Neri, Chairman, Sugar Company donated the chocolate bars, but had no part in funding; funding by USDA