Studies related to Liver Enzymes and Kava

The Kava Anxiety Depression Spectrum Study (KADSS): A Randomized, Placebo-controlled Crossover Trial Using An Aqueous Extract Of Piper Methysticum

Effect None
Trial Design Double blind
Trial Length 2-4 Weeks
Number of Subjects 60
Sex Both Genders
Age Range 18-29, 30-44, 45-64
Notes for this study:
Over a period of 3 weeks active treatment (one week run in phase),16g of Kava standardized to 250mg of activa kavalactones daily (2/5ths in the morning and afternoon, 1/5th in the evening) as an aqueous extract was able to exert anxiolytic and anti-depressive actions in persons with at least one month of higher but stable anxiety levels.

No hepatotoxic signs noted via clinical assessment, liver enzymes not measured.

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