Studies related to Oxidation of LDL and Hesperidin

Glucosyl Hesperidin Lowers Serum Triglyceride Level In Hypertriglyceridemic Subjects Through The Improvement Of Very Low-density Lipoprotein Metabolic Abnormality

Effect Decrease
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 25
Sex Male
Age Range 18-29, 30-44, 45-64
Body Types Overweight, Average
Notes for this study:
500mg of G-hesperidin daily taken prior to bedtime for 24 weeks in hyperlipidemic patients was able to suppress triglycerides in serum up to 34%, but this suppression was normalized upon 4 weeks of cessation which returned to normal levels and only occurred in those with a baseline TG value above 150mg/dL. HDL was unaffected, while total cholesterol and LDL were mildly decreased and normalized to baseline upon cessation of the supplement, and the particule size of LDL was increased (suggesting a reduction in the atherogenic small and oxidized LDL).