Herbal Ephedra/caffeine For Weight Loss: A 6-month Randomized Safety And Efficacy Trial
| Effect | Increase |
| Trial Design | Double blind |
| Trial Length | n/a |
| Number of Subjects | 167 |
| Sex | n/a |
Over a period of 6 months, ephedrine/caffeine at 90mg/192mg daily (from Ma Huang and Kola Nut) reduced body weight by 5.6kg while placebo induced 2.6kg weight loss.
LDL cholesterol was reduced by 8mg/dl in EC group and HDL cholesterol increased by 2.7mg/dl. Placebo did not see changes.
Small increases in blood pressure and heart rate were seen, but of minor significance. Compliance was similar in both groups.
