Zinc Monotherapy Increases Serum Brain-derived Neurotrophic Factor (BDNF) Levels And Decreases Depressive Symptoms In Overweight Or Obese Subjects: A Double-blind, Randomized, Placebo-controlled Trial
|Trial Design||Double blind|
|Trial Length||1-6 months|
|Number of Subjects||46|
|Age Range||18-29, 30-44|
Supplementation of zinc (30mg elemental) for 12 weeks in obese persons with depressive symptoms according to the BDI II rating scale was able to improve symptoms more than placebo; this improvement in depressive symptoms occurred alongside increases in serum BDNF concentrations.