Studies related to Lean Mass and HMB

Effects of Calcium β-HMB Supplementation During Training on Markers of Catabolism, Body Composition, Strength and Sprint Performance
Effect None
Trial Design doubleblind
Trial Length 24weeks
Number of Subjects 28
Gender m
Notes for this study:
In 28 elite football players (NCAA division) given a drink mixture (taurine, glucose, potassium phosphate and disodium phosphate) with or without 3g additional HMB for 28 days, the addition of HMB failed to influence any measured parameter (either biochemical or sprint/power testing).

Beta-hydroxy-beta-methylbutyrate Ingestion, Part I: Effects On Strength And Fat Free Mass

Effect Increase
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 37
Gender Male
Age Range 18-29
Body Types Untrained, Average
Notes for this study:
38mg/kg HMB supplementation (approximately 3g daily) and double that dose were given to untrained persons alongside a resistance training program for 8 weeks. Peak isometric and isokinetic torque was (sporadically) higher in HMB supplemented groups relative to placebo while the 1 rep max testing failed to show significant differences (trended towards an increase), only the 38mg/kg group exhibited increases in lean mass.

Effects Of Calcium Beta-hydroxy-beta-methylbutyrate (HMB) Supplementation During Resistance-training On Markers Of Catabolism, Body Composition And Strength

Effect None
Trial Design Double blind
Trial Length 2-4 Weeks
Number of Subjects 40
Gender Male
Age Range 18-29
Body Types Trained, Average
Notes for this study:
3g or 6g HMB daily (within a carbohydrate and protein shake, of which was also given to placebo) during a resistance training protocol in trained men for 28 days failed to exert any significant benefits.

Effect of β-hydroxy-β-methylbutyrate Supplementation During Energy Restriction in Female Judo Athletes
Effect None
Trial Design cohort
Trial Length 1week
Number of Subjects 8
Gender f
Notes for this study:
3g of HMB for 3 days during caloric restriction in trained athletes failed to preserve lean mass or preserve power but increased fat mass loss. Small powered study.

The Effect Of HMB Supplementation On Body Composition, Fitness, Hormonal And Inflammatory Mediators In Elite Adolescent Volleyball Players: A Prospective Randomized, Double-blind, Placebo-controlled Study

Effect Increase
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 29
Gender Both Genders
Age Range 13-17
Body Types Trained, Average
Notes for this study:
In exercising youth (aged 13.5-18), HMB supplementation at 3g daily was able to increase lean mass more than placebo over a period of 7 weeks alongside training which was associated with an improvement in power output only on leg curls (leg extensions and arm exercises had no significant increase, and when pooled together the increases weren't significant) yet an increase in power output on a Wingate test.

Body Composition In 70-year-old Adults Responds To Dietary Beta-hydroxy-beta-methylbutyrate Similarly To That Of Young Adults

Effect None
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 31
Gender Both Genders
Age Range 65+
Body Types Average
Notes for this study:
In older individuals (70yrs) HMB was able to slightly increase lean mass (not statistically significant) by 0.8kg over a period of 8 weeks when combined with resistance training. Fat Mass was unchanged by weight, but appeared to have reduced area (size), and power appeared to be increased on a lat pulldown test but not other tests.

Beta-hydroxy-beta-methylbutyrate (HMB) Supplementation Does Not Affect Changes In Strength Or Body Composition During Resistance Training In Trained Men

Effect None
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 34
Gender Male
Age Range 18-29
Body Types Trained
Notes for this study:
3g HMB for 6 weeks in resistance trained men failed to result in changes to lean mass, power output, or fat mass.

Effects Of Nine Weeks Of Beta-hydroxy-beta- Methylbutyrate Supplementation On Strength And Body Composition In Resistance Trained Men

Effect None
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 22
Gender Male
Age Range 18-29
Body Types Trained, Average
Notes for this study:
In resistance trained men, HMB failed to increase overall strength (despite increasing leg extension significantly) and trended to decrease fat mass while increasing lean mass; overall food intake appeared to also increase with HMB supplementation.