Lipid-lowering And Anti-inflammatory Effects Of Tetradecylthioacetic Acid In HIV-infected Patients On Highly Active Antiretroviral Therapy
Notes for this study:
|Number of Subjects
In persons with HIV who were already on anti-viral therapy, controlling the diet and then supplementing TTA (1,000mg in four divided doses for four weeks) exerted hypolipidemic and anti-inflammatory properties yet did not influence viral loads in the tested immune cells. No placebo group was used.
The decrease in apolipoprotein B was trending to, but did not reach, statistical significance (P = 0.08). The decrease in triglycerides seen was not additive with the dietary treatment and was not seen as evidence for the efficacy of TTA.