Cardiovascular Effects Of Prolonged Delta-9-tetrahydrocannabinol Ingestion

Effect Increase
Trial Design Cohort
Trial Length 1-2 Weeks
Number of Subjects 14
Sex Male
Age Range 18-29, 30-44
Notes for this study:
Chronic administration of THC ingestion in hospitalized volunteers was associated with a reduction in heart rate after the initial increase observed with THC, and a reduction in blood pressure was also noted.

Orthostatic hypotension was also noted acutely, but subjects became tolerant to this effect of THC even when the peripheral hypotension was still present. Tolerance was associated with an increase in total body water and weight.

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