Lack Of Analgesia By Oral Standardized Cannabis Extract On Acute Inflammatory Pain And Hyperalgesia In Volunteers
Notes for this study:
|Number of Subjects
In 18 otherwise healthy female volunteers who ingested 20mg THC with a meal and then were tested on various pain tests, there was a failure for THC to reduce pain in a capsaicin intradermal test (2.5 hours after ingestion) despite this being in the time range of peak plasma THC concentrations (2-4 hours). The pain associated with a sunburn test was also not affected any differently than placebo.
This dose of cannabis did not affect blood pressure (despite an increase in heart rate) and had psychoactive effects.