| Effect | Increase |
| Trial Design | Double blind |
| Trial Length | 1-6 months |
| Number of Subjects | 630 |
| Sex | Both Genders |
| Age Range | 45-64, 65+ |
| Body Types | Average |
In persons with multiple sclerosis given either pure THC or cannabis extracts over 15 weeks, supplementation failed to result in any improvements in physician-assessed physical mobility although patient-reported stiffness, pain, spasticity, and spasms (but not shake/tremor) appeared to be improved with supplementation. This led to improvements in sleep quality, although symptoms of fatigue and depression were unaffected.
