Effect Of Delta-9-tetrahydrocannabinol And Cannabidiol On Nocturnal Sleep And Early-morning Behavior In Young Adults
Notes for this study:
||min. Placebo: 10.15 Low dose: 7.97 High dose: 9.31
|Number of Subjects
In a randomized, double-blind, placebo-controlled crossover trial, 8 participants took 15 mg of THC and CBD, 5 of both, only 15 mg of THC, or placebo via oral spray before bed on 4 consecutive nights, with at least a week between treatments.
Funding issues for this study:
There was a statistically significant increase in fatigue and reduction in mood for the high dose combination group but not the low dose group. There was a statistically significant improvement in reaction time on digit memory recall but not an improvement of accuracy in the low-dose comnbination group.
There wasn't a statistically significant difference for sleep latency, digit symbol substituent, choice reaction time, sustained attention, immediate word recall, delayed word recall, sex-letter memory recall for the combination groups.
The study was sponsored by GW Pharmaceuticals plc