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Studies related to Symptoms of Diabetic Neuropathy and Cannabis

Efficacy Of Inhaled Cannabis On Painful Diabetic Neuropathy

Effect Decrease
Trial Design Randomized trial
Trial Length 24 hours
Number of Subjects 16
Sex Both Genders
Notes for this study:
In a randomized, double-blind, placebo-controlled crossover trial, 16 participants with diabetic peripheral neuropathic pain smoked low (1%), medium (4%) or high (7%) dose cannabis, or placebo, acutely on 4 different occasions and monitored for 240 minutes.

The high dose group saw statistically significant differences in spontaneous compared with placebo after 15, 30, and 45 minutes, but not longer, while the low and medium dose groups didn't see a statistically significant difference, though the medium group generally saw less pain. The was the same for evoked pain, but the only statistically significant difference was at 30 minutes for the high dose group (foam brush) while the difference was statistically significant at 5, 30, and 45 minutes for von Frey method.

Euphoria and somnolence were both higher in the high dose group.

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