Oral THC:CBD Cannabis Extract For Refractory Chemotherapy-induced Nausea And Vomiting: A Randomised, Placebo-controlled, Phase II Crossover Trial
Notes for this study:
|Number of Subjects
In a randomized, placebo-controlled trial, 81 participants with refractory chemotherapy-induced nausea and vomiting took a self-determined dose of THC and CBD (on average about 5 mg of both THC and CBD) 3 times daily or placebo for 5 days before crossing over for another 5 days.
The number of participants with a complete response, no vomiting, no use of rescue medications, no significant nausea was higher when taking cannabis. Mean scores for these parameters were statistically significantly improved as well.
Sedation and dizziness were the cannabis-related side-effects most prevalent. Quality of life generally improved.