Studies related to Opioid Use and Cannabis

Effect Of Inhaled Cannabis For Pain In Adults With Sickle Cell Disease: A Randomized Clinical Trial

Effect Decrease
Trial Design Randomized trial
Trial Length 1-7 Days
Number of Subjects 27
Sex Both Genders
Notes for this study:
In a randomized, double-blind, placebo-controlled crossover trial, 27 participants with pain due to sickle cell disease inhaled vaporized cannabis leaf containing 4.4% THC and 4.9% CBD or placebo 3 times daily for 5 days.

There wasn't a statistically significant difference for pain during the 5 days from daily subjective eatings. There weren't statistically significant differences in pain during general activity, walking, working, or interference with enjoyment, sleep, or mood, though the cannabis group did see a greater reduction. There wasn't a statistically significant change in opioid use.

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