| Effect | Increase |
| Trial Design | Double blind |
| Trial Length | 24 hours |
| Number of Subjects | 12 |
| Sex | Male |
| Age Range | 18-29, 30-44 |
| Body Types | Average |
Chewing gum containing 1-2mg of nicotine acutely in otherwise healthy men is able to increase metabolic rate as assessed via indirect calorimetry by 3.7-4.9% (AUC values over the course of 180 minutes) relative to placebo gum. Fat oxidation rates were not significantly influenced.
