Studies related to Homocysteine and Vitamin B₁₂

A Vitamin B-12 Supplement Of 500 μg/d For Eight Weeks Does Not Normalize Urinary Methylmalonic Acid Or Other Biomarkers Of Vitamin B-12 Status In Elderly People With Moderately Poor Vitamin B-12 Status

Effect Decrease
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 100
Sex Both Genders
Age Range 65+
Body Types Overweight
Notes for this study:
8 weeks supplementation of 10, 100, or 500mcg of B12 as cyanocobalamin in deficient or borderline deficient adults was able to reduce plasma homocysteine (at only the two higher dosages) and normalized biomarkers of deficiency in most subjects, but was unable to benefit all subjects at even the highest dose.