| Effect | None |
| Trial Design | Double blind |
| Trial Length | 6+ Months |
| Number of Subjects | 144 |
| Sex | Both Genders |
| Age Range | 45-64, 65+ |
| Body Types | Obese |
In persons with impaired glucose tolerance where 6.4g L-arginine was given daily for 18 months (followed by 12 months of followup), supplementation was associated with improved fat mass and lean mass (increase in lean mass was 0.12+/-1.97, and only statistically significant when compared to the loss seen with placebo) and associated with improved insulin secretion following a test meal. Insulin sensitivity increased by Strumvall but not HOMA-IR, and fasting blood flow and glucose were unaltered.
