Effect | Decrease |
Trial Design | Double blind |
Trial Length | 1-6 months |
Number of Subjects | 39 |
Sex | Both Genders |
Age Range | 45-64, 65+ |
Body Types | Overweight |
Supplementation of 8g of arginine twice daily (16g total) for 6 weeks in persons with intermittent claudication appears to promote blood flow and reduce symptoms associated with increased biomarkers of nitric oxide metabolite (nitrate and urinary cGMP). Functional testing noted that arginine outperformed 80mcg PGE1 in improving walking distance and pain-free walking distance, and improved VAS scores for symptoms.