Effect Of A Long-term Oral L-arginine Supplementation On Glucose Metabolism: A Randomized, Double-blind, Placebo-controlled Trial
Notes for this study:
|Number of Subjects
In persons with impaired glucose tolerance where 6.4g L-arginine was given daily for 18 months (followed by 12 months of followup), supplementation was associated with improved fat mass and lean mass (increase in lean mass was 0.12+/-1.97, and only statistically significant when compared to the loss seen with placebo) and associated with improved insulin secretion following a test meal. Insulin sensitivity increased by Strumvall but not HOMA-IR, and fasting blood flow and glucose were unaltered.