Studies related to Estrogen and Coenzyme Q10

Hormonal And Metabolic Effects Of Coenzyme Q10 And/or Vitamin E In Patients With Polycystic Ovary Syndrome

Effect Increase
Values Estradiol. Mean and SD. Placebo: before 74.43 ± 17.95 , after 71.09 ± 12.38 . Coq10: before 61.07 ± 12.88 , after 95.75 ± 13.7 . Vitamin E: before 85.45 ± 17.79 , after 99.66 ± 23.01. Combination: before 91.85 ± 28.16, after 101.65 ± 30.7.
Trial Design Randomized trial
Trial Length 1-6 months
Number of Subjects 86
Sex Female
Notes for this study:
In a randomized, double-blind, placebo-controlled trial, 86 participants with polycystic ovary syndrome were allocated to take placebo, 200 mg of coq10, 400 IU of vitamin E, or the combination daily for 8 weeks.

Progesterone level was the primary outcome, and there was a notable increase in the coq10 group but not the placebo group. There was also a considerable increase in estradiol, a decrease in testosterone, an increase in sex hormone-binding globulin, and a reduction in luteinizing hormone, with no change follicle-stimulating hormone. There was a statistically significant reduction in fasting blood sugar, insulin, and insulin resistance, which was greater than placebo.