| Effect | Decrease |
| Trial Design | Double blind |
| Trial Length | n/a |
| Number of Subjects | 20 |
| Gender | n/a |
CoQ10 supplementation in a population of persons with fibromyalgia given 300mg daily for 3 months was able to reduce levels of lipid peroxidation and pro-oxidative markers in the serum, and vicariously though this (hypothesized due to correlations) reductions were seen in headaches associated with fibromyalgia by correcting abnormal markers of metabolism.
| Effect | Decrease |
| Trial Design | Double blind |
| Trial Length | n/a |
| Number of Subjects | 56 |
| Gender | n/a |
In persons with ischaemic left ventricular systolic dysfunction given 300mg CoQ10 daily for 8 weeks, an improvement in blood flow from endothelial function was seen and possibly was due to a reduction in lipid peroxidation (as assessed by correlation, causation not shown).
No effects on markers of diabetic health or other markers of heart health were seen.
| Effect | Decrease |
| Trial Design | Double blind |
| Trial Length | n/a |
| Number of Subjects | 47 |
| Gender | n/a |
In persons with idiopathic oligoasthenoteratozoospermia (basically bad sperm quality resulting in infertility), usage of 200mg of CoQ10 daily for 12 weeks was associated with a reduction in oxidative stress as measured in the semen, but did not increase any parameters of the semen such as motility or count.
| Effect | Decrease |
| Trial Design | Double blind |
| Trial Length | n/a |
| Number of Subjects | 18 |
| Gender | n/a |
After supplementation of 100mg CoQ10 daily, serum levels of CoQ10 were increased while they were decreased in the placebo group due to exercise. Normalized oxidation rates were seen with CoQ10 while increases in oxidation and lipid peroxidation were seen in placebo.
Despite the above beneficial trends, no significant effects on exercise performance were noted.
