Studies related to Leptin and Coenzyme Q10

Effects Of Coenzyme Q10 Supplementation On Serum Values Of Adiponectin, Leptin, 8-isoprostane And Malondialdehyde In Women With Type 2 Diabetes

Effect Decrease
Values (ug/mL). Mean and SEM. Placebo: before 22.18 ± 2.11, after 24.29 ± 2.27. Intervention: before24.84 ± 2.09, after 22.69 ± 2.03.
Trial Design Randomized trial
Trial Length 1-6 months
Number of Subjects 74
Sex Both Genders
Notes for this study:
In a randomized, double-blind, placebo-controlled trial 74 participants with type 2 diabetes took 100 mg of coq10 daily or placebo for 12 weeks.

There was a statistically significantly greater reduction in total cholesterol, malondialdehyde and a significantly greater increase in adiponectin than placebo. While not statistically significant, the coq10 group saw a greater improvement in fasting glucose, HbA1c, insulin, triglycerides, LDL, leptin, 8-Isoprostane, and insulin resistance.