Effect Of Coenzyme Q10 Supplementation On Antioxidant Enzymes Activity And Oxidative Stress Of Seminal Plasma: A Double-blind Randomised Clinical Trial
Notes for this study:
||(x10⁶ ml⁻¹). Change. Mean and SD. Placebo: -3.56 (14.96) Intervention: 1.34 (13.66)
|Number of Subjects
In a randomized, double-blind, placebo-controlled trial 60 infertile men with idiopathic oligoasthenoteratozoospermia were allocated to take 200 mg of coenzyme q10 or placebo daily for 3 months.
47 participants completed the study and were analyzed. While the placebo group saw a reduction in sperm count, the coq10 group saw a small increase, the difference not being statistically significant. Motility saw a small, nonsignificant improvement, while morphology saw a small, nonsignificant worsening. There was a statistically significant reduction in lipid peroxidation and an increase in superoxide dismutase and catalase in the intervention group.