Betaine Supplementation Decreases Plasma Homocysteine Concentrations But Does Not Affect Body Weight, Body Composition, Or Resting Energy Expenditure In Human Subjects
Notes for this study:
|Number of Subjects
In obese subjects given supplementation of betaine at 6g daily for 12 weeks was able to decrease homocysteine (9%) relative to placebo but the decrease in total cholesterol and LDL seen in placebo was not present in betaine intervention; there was no influence on body weight. There was no influence on plasma nor RBC folate concentrations.
The increase in ALP (liver enzyme) seen in placebo was prevented with betaine.