| Effect | Decrease |
| Trial Design | Double blind |
| Trial Length | 1-6 months |
| Number of Subjects | 45 |
| Sex | Both Genders |
| Age Range | 45-64, 65+ |
In subjects either with dry mouth symptoms or healthy controls, a toothpaste containing 4% betaine over the course of six weeks was noted to reduce dry mouth symptoms in persons with dry mouth (beneficially affecting 44% of persons, a level significantly greater than placebo toothpaste) and appeared to have its efficacy reduced in the presence of 1% sodium lauryl sulfate (SLS).
