| Effect | Decrease |
| Trial Design | Cohort |
| Trial Length | 6+ Months |
| Number of Subjects | 7 |
| Sex | Both Genders |
| Age Range | 30-44, 45-64 |
| Body Types | Overweight |
Supplementation of betaine at 500mg twice daily over the course of one year was able to fully normalize liver enzymes in three out of seven patients and reduce them by more than 50% in three others, with one nonresponder and the dropouts (before the year the trial lasted) also noting a 38-39% reduction.
