Studies related to Training Volume and Trimethylglycine

The Effects Of Chronic Betaine Supplementation On Exercise Performance, Skeletal Muscle Oxygen Saturation And Associated Biochemical Parameters In Resistance Trained Men

Effect Increase
Trial Design Double blind
Trial Length 1-2 Weeks
Number of Subjects 13
Sex Male
Age Range 18-29
Body Types Trained, Average
Notes for this study:
Supplementation of 2.5g TMG with 500mL gatorade in resistance trained men for two weeks appears to (in a fasted condition following a final 1.25g dose) increase work volume conducted on the bench press during the workout by 6.5%, although the increase of reps during any particular set or maximal power output were not affected.

The increase in lactate production seen in placebo (270%) was attenuated with betaine (210%), but lipid peroxidation (MDA) and nitric oxide (assessed by NOx) were unaffected.
Funding issues for this study:
Supported by Danisco and The University of Memphis