Studies related to Creatinine and Trimethylglycine

Betaine Supplementation Decreases Plasma Homocysteine Concentrations But Does Not Affect Body Weight, Body Composition, Or Resting Energy Expenditure In Human Subjects

Effect None
Trial Design Double blind
Trial Length 6+ Months
Number of Subjects 42
Sex Both Genders
Age Range 18-29, 30-44
Body Types Obese
Notes for this study:
In obese subjects given supplementation of betaine at 6g daily for 12 weeks was able to decrease homocysteine (9%) relative to placebo but the decrease in total cholesterol and LDL seen in placebo was not present in betaine intervention; there was no influence on body weight. There was no influence on plasma nor RBC folate concentrations.

The increase in ALP (liver enzyme) seen in placebo was prevented with betaine.