Effect of Folic Acid and Betaine Supplementation on Flow-Mediated Dilation: A Randomized, Controlled Study in Healthy Volunteers
Notes for this study:
| Effect | None |
| Trial Design | Double blind |
| Trial Length | 1-6 months |
| Number of Subjects | 39 |
| Sex | Both Genders |
| Age Range | 45-64, 65+ |
| Body Types | Overweight |
Six weeks supplementation of 6g TMG in otherwise healthy adults (aged 50-70) was sufficient to lower fasting plasma homocysteine (12%) which underperformed relative to 800mcg folic acid; blood flow was unaffected. Serum B12 was not affected relative to placebo, but due to a nonsignificant drop in folate and a nonsignificant rise in the TMG group there was a difference between them.
