Studies related to and

Oral Zinc In Acne Vulgaris: A Clinical And Methodological Study

Effect Decrease
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 54
Gender Both Genders
Age Range 13-17, 18-29
Notes for this study:
Supplementation of 600mg zinc sulphate daily (132mg elemental zinc) over the course of six months appears to be associated with a modest but significantly greater reduction in acne than does placebo.

Low Doses Of Zinc Gluconate For Inflammatory Acne

Effect Decrease
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 20
Gender Both Genders
Age Range 13-17, 18-29
Notes for this study:
Supplementation of 200mg zinc gluconate (30mg elemental zinc) appears to be more effective than placebo in reducing symptoms of inflammatory acne.

Oral Zinc Sulphate Therapy In Acne Vulgaris: A Double-blind Trial

Effect Decrease
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 56
Gender Both Genders
Age Range 13-17, 18-29
Notes for this study:
Supplementation of 600mg zinc sulphate daily over the course of 12 weeks was associated with significant improvements in 58% of persons using zinc, which was greater than the response rate seen in placebo. This was thought to be related to an increase in serum vitamin A.

Multicenter Randomized Comparative Double-blind Controlled Clinical Trial Of The Safety And Efficacy Of Zinc Gluconate Versus Minocycline Hydrochloride In The Treatment Of Inflammatory Acne Vulgaris

Effect Decrease
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 332
Gender Both Genders
Age Range 13-17, 18-29
Notes for this study:
Supplementation of 30mg elemental zinc (as gluconate) daily for a period of three months with the primary endpoint of a 66% reduction in symptoms noted that 31.2% of the zinc group was able to meet the aforementioned criteria. The reference drug, Minocycline, outperformed zinc when used at 100mg by benefiting 63.4% of the group.