Effects Of Rhodiola Rosea Supplementation On Mental Performance, Physical Capacity, And Oxidative Stress Biomarkers In Healthy Men
Notes for this study:
||(nmol/L). Mean and SD. Placebo: At rest, before 24.7 ± 2.1, after 26.5 ± 2.5. Post exercise: before 23.4 ± 2.3, after 27.8 ± 2.5. 24H: before 24.7 ± 2.2, after 26.3 ± 2.8. Rhodiola: At rest, before 21.7 ± 2.2, after 21.6 ± 1.2. Post exercise: before 19.8 ± 1.9, after 23.9 ± 1.7. 24H: before 22.5 ± 2.1, after 23.7 ± 1.3.
|Number of Subjects
In a randomized, double-blind, placebo-controlled trial, 26 healthy participants were allocated to take 600 mg of a Rhodiola Rosea extract (3% rosavins) or placebo daily for 4 weeks.
Simple reaction time improved somewhat when taking Rhodiola, though the difference wasn't statistically significant compared with placebo, and accuracy for choice reaction was also nonsignificantly improved. Blood lactate was reduced significantly at rest and nonsignificantly at max during an exercise trial (cycle ergometer). Heart rate was unaffected. There was a small, nonsignificant improvement in power and time to exhaustion, while VO2peak was unaffected.
Compared with placebo, there were no statistically significant differences in the change for cortisol, testosterone, growth hormone, creatine kinase, lipid hydroperoxides, superoxide dismutase, and total antioxidant capacity, though total antioxidant capacity was nonsignificantly increased, and cortisol after exercise was nonsignificantly decreased.