Rhodiola Rosea For Mental And Physical Fatigue In Nursing Students: A Randomized Controlled Trial
Notes for this study:
||RAND-36 subscale. Mean and SE. Placebo: before 81.6 (4.7), after 90.2 (6.8). Rhodiola: before 78.0 (4.5), after 71.8 (6.1).
|Number of Subjects
||18-29, 30-44, 45-64
In a randomized, double-blind, placebo-controlled trial, 48 nursing students were allocated to take placebo or 364 mg of Rodiola Rosea twice daily for 42 days.
Funding issues for this study:
The primary outcome was a reduction in fatigue, and there was a statistically significantly greater reduction in the Rhodiola group than the placebo group in the vitality subscale of RAND-36, but less of a reduction on a visual analog scale.
There were no statistically significant differences in the change between groups on the RAND-36 scale for physical functioning, role limitations due toi physical health, pain, and social functioning, while the Rhodiola group reported worse general health, emotional wellbeing, and role limitation due to emotional problems, the first being statistically significant and the latter being p=0.052 and 0.051.
There were no notable differences in adverse events between groups.
"This project was funded by the Alberta Agriculture and Rural Development, Government of Alberta, through AVAC Ltd. The funder developed and prepared the trial intervention, but had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; and preparation, review, or approval of the manuscript."