Treatment Of Metabolic Acidosis In Patients With Stage 3 Chronic Kidney Disease With Fruits And Vegetables Or Oral Bicarbonate Reduces Urine Angiotensinogen And Preserves Glomerular Filtration Rate

Effect None
Values Before/After estimated GFR: decreased in usual care group (42.6±7.6 to 28.8±7.3); increased with NaHCO3 supplement (42.6±7.0 to 35.2±6.9); and increased with fruits and vegetables ( 42.3±7.1 to 36.9±6.7)
Trial Design Randomized trial
Trial Length 6+ Months
Number of Subjects 108
Sex Both Genders
Age Range 45-64
Body Types Obese, Overweight, Average
Notes for this study:
This was a 3-year trial that randomized 108 people with stage-3 chronic kidney disease and mild metabolic acidosis (22 mmol/l < plasma TCO2 < 24 mmol/l) to three different groups: added fruit and vegetables, oral NaHCO 30.3 mEq/Kg in three divided doses per day, and usual care.