Treatment Of Metabolic Acidosis In Patients With Stage 3 Chronic Kidney Disease With Fruits And Vegetables Or Oral Bicarbonate Reduces Urine Angiotensinogen And Preserves Glomerular Filtration Rate

Effect Increase
Values Before/after for usual care: -0.6±0.6. Before/after for NaHCO3 supplement: +0.9±0.6. Before/after for fruit & vegetable diet: +0.9±0.6
Trial Design Randomized trial
Trial Length 6+ Months
Number of Subjects 108
Sex Both Genders
Age Range 45-64
Body Types Obese, Overweight, Average
Notes for this study:
This was a 3-year trial that randomized 108 people with stage-3 chronic kidney disease and mild metabolic acidosis (22 mmol/l < plasma TCO2 < 24 mmol/l) to three different groups: added fruit and vegetables, oral NaHCO 30.3 mEq/Kg in three divided doses per day, and usual care.