Oral L-citrulline Malate In Patients With Idiopathic Pulmonary Arterial Hypertension And Eisenmenger Syndrome: A Clinical Trial
Notes for this study:
||6 minute walking time. Mean and 95% CI. Change from baseline. −44.1 (−73.2 to −15.1)
|Number of Subjects
In this randomized, uncontrolled trial, 25 participants with pulmonary hypertension were given 3 g of citrulline malate daily for 2 weeks.
The primary outcome was the change in exercise capacity, and there was a statistically significant improvement in 6 minute walking distance. There was also an improvement in pulmonary arterial pressure, and quality of life.