Efficacy And Safety Of A Butcher's Broom Preparation (Ruscus Aculeatus L. Extract) Compared To Placebo In Patients Suffering From Chronic Venous Insufficiency

Effect Decrease
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 110
Sex Female
Age Range 30-44, 45-64, 65+
Body Types Average
Notes for this study:
12 weeks supplementation of a _ruscus aculeatus_ extract at 36-37.5mg of a 15-20:1 concentration in women with chronic venous insufficiency was able to reduce lower limb circumference (anti-edemic actions in the leg and ankles) while improving global symptoms of CVI, although it did not have any efficacy on quality of life relative to placebo.