Is sugar more filling than HFCS?

No.[1][2][3][4][5]

No differences in leptin or satiety have been found between the two.


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References

  1. Melanson KJ, et al Effects of high-fructose corn syrup and sucrose consumption on circulating glucose, insulin, leptin, and ghrelin and on appetite in normal-weight women . Nutrition. (2007)
  2. Monsivais P, Perrigue MM, Drewnowski A Sugars and satiety: does the type of sweetener make a difference . Am J Clin Nutr. (2007)
  3. Soenen S, Westerterp-Plantenga MS No differences in satiety or energy intake after high-fructose corn syrup, sucrose, or milk preloads . Am J Clin Nutr. (2007)
  4. Melanson KJ, et al High-fructose corn syrup, energy intake, and appetite regulation . Am J Clin Nutr. (2008)
  5. Stanhope KL, et al Twenty-four-hour endocrine and metabolic profiles following consumption of high-fructose corn syrup-, sucrose-, fructose-, and glucose-sweetened beverages with meals . Am J Clin Nutr. (2008)