The Nutrition Examination Research Digest (NERD) aims to provide rigorous, unbiased analysis of the latest and most important nutrition and supplementation studies. Click here to subscribe or login if already a subscriber .

In this article

Deep Dive: What happens when you eat as much as possible?

Joey Chestnut may not have too much to worry about, but Nathan's should confirm these results by sponsoring a follow-up involving hot dogs, not pizza.

Study under review: Physiological responses to maximal eating in men

Introduction

Obesity is the result of a chronic positive energy balance, in which more energy is absorbed than expended. Part of the problem with the current approach to mitigating obesity, besides the fact that it is a multifactorial disease, is determining why some people, but not all, overeat. Although it is pretty well agreed upon[1] that over consumption of food is the result of many factors, studies have shown[2] that people normally tend to compensate for overfeeding periods and lose the weight gained afterward in an unconscious manner. Understanding the differences between people who can and people who can’t compensate requires a careful examination of the physiology of overfeeding.

There have been many studies over the years testing different types of diets for weight loss, both under very controlled conditions and under free-living scenarios. However, the physiological response to maximal overfeeding (i.e. eating as much as possible) has received comparably less attention. Moreover, most of the previous long-term overfeeding studies[3] have analyzed the effects of prescribed overfeeding, in which participants are given a specific energy intake goal that is above their energy requirements. So, it is not known precisely how the body deals with maximal eating and the physiological responses to it.

The authors of this study wanted to compare and characterize the acute participant response to two types of feedings: participants eating until they were comfortably full and participants eating as much as they possibly could.

Obesity results from the chronic overconsumption of calories, which is caused by several environmental factors. However, normal weight participants appear to compensate for overfeeding, so it is not completely understood why some people do not compensate for an increase in energy intake over time. Moreover, the physiological response to eating as much as possible has not been yet determined.

What was studied?

Become a subscriber to the Nutrition Examination Research Digest to read the full article.

Becoming a member will keep you updated on the most important nutrition studies every month, and give you access to our back catalog of over 500 other articles.

NERD also includes access to Examine Personalized, which includes 150+ monthly summaries on the most important recent studies and access to our database of 10,000+ studies across 600+ health topics.

Stop wasting time and energy — we make it easy for you to stay on top of nutrition research

Try free for a week

Already a member? Please login to read this article.

What were the findings?

Subscribe to the Nutrition Examination Research Digest to unlock this article.

Free 7-day trial!

Already a member? Please login to read this article.

The bigger picture

Subscribe to the Nutrition Examination Research Digest to unlock this article.

Already a member? Please login to read this article.

Frequently asked questions

Subscribe to the Nutrition Examination Research Digest to unlock this article.

Already a member? Please login to read this article.

What should I know?

Subscribe to the Nutrition Examination Research Digest to unlock this article.

Already a member? Please login to read this article.

Other Articles in Issue #70 (August 2020)