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Evaluating the efficacy of vitamin D, omega-3, and strength training in older adults

This large and meticulously designed trial explored whether supplementation or strength training improved the mental or physical health of people over 70. It came up empty-handed. The question is: why?

Study under review: Effect of Vitamin D Supplementation, Omega-3 Fatty Acid Supplementation, or a Strength-Training Exercise Program on Clinical Outcomes in Older Adults: The DO-HEALTH Randomized Clinical Trial

What was the question?

Is there any effect of vitamin D and omega-3 supplementation, or strength training alone or in combination, on blood pressure, nonvertebral bone fractures, physical performance, infection rate or cognition?

Why was the question worth asking?

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How was the question answered?

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What was the answer?

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How much should you trust the answer?

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What’s the take-home?

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Other Articles in Issue #76 (February 2021)