Study under review: Remission of prediabetes to normal glucose tolerance in obese adults with high protein versus high carbohydrate diet: randomized control trial
Obesity and diabetes are major issues in the developed and developing world. Diabetes, once it manifests, can wreak havoc on circulation and cause a variety of complications, such as those shown in Figure 1. Diabetes is currently the 7th leading cause of death in the United States and the prevalence of both diabetes and prediabetes is on the rise.
One way to help prevent diabetes is to identify people at risk by screening for a condition called “prediabetes.” Prediabetes is a condition characterized by higher than usual levels of fasting blood sugar, though not high enough to be called diabetes. This includes a fasting blood sugar of 100 – 125 milligrams per deciliter (mg/dL) or an “anytime” blood sugar of 140-199 mg/dL. It can also be diagnosed if glycated hemoglobin (Hb A1c) is between 5.7-6.4%.
Most people diagnosed with prediabetes will develop diabetes within the next 10 years. However, if caught early, prediabetes and even early Type II diabetes can be reversed.
Two of the best ways to improve glycemic control and insulin sensitivity are to exercise and lose weight. Naturally, many people who find out they have prediabetes want to alter their lifestyle to reduce their risk of developing diabetes. But, is there a way to tweak a healthy diet to further reduce the risk of diabetes?
The following study, from researchers at the University of Tennessee, sought to examine just that. Following a study the same authors published in 2013, showing that a high protein, low calorie diet improved insulin sensitivity in obese adults without diabetes or prediabetes, they wanted to determine how the same intervention might work in a population that had prediabetes.
The current study examined whether replacing some carbohydrate with protein could have positive outcomes on metabolic syndrome and glycemic control in obese patients with prediabetes.
Other Articles in Issue #28 (February 2017)
Protein for hypertension: the whey to go?
Dairy has been linked to lower blood pressure. But can a high intake of whey protein, without the rest of the dairy components, show a benefit as well?
The mindfulness-body connection
Health, and health-promoting habits, are massively influenced by how you think. This systematic review looked at mindfulness interventions, to see if they led to weight loss and psychological benefits.
Interview: Bill Willis, PhD
Bill is one of the few researchers who's actively competed in bodybuilding. Plus he researches muscle repair!
Coconut water ... overhyped and understudied?
Coconut water is slowly taking over grocery store aisles, with some athletes using it as a beverage of choice for hydration. This study looks at how well it actually performs for hydration during exercise
Oiling up arthritic joints
There have been many, many randomized trials done on fish oil and other marine oils, looking at their effects on arthritis. But when you look at all the trials together, what's the verdict?
SCD for IBD?
Crohn's Disease and Ulcerative Colitis are difficult to treat, to say the least. Many have anecdotally found success with the Specific Carbohydrate Diet, which is tested more rigorously in this trial.
Interview: Dana Ellis Hunnes, PhD, MPH, RD
Are you considering adopting a plant-based diet? Dr. Hunnes gives both a global and personal view.