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Gut bugs and fiber: A novel way to keep dyslipidemia at bay?

A systematic review and meta-analysis of the prebiotics and synbiotics effects on glycaemia, insulin concentrations and lipid parameters in adult patients with overweight or obesity.

Study under review: A systematic review and metaanalysis of the prebiotics and synbiotics effects on glycaemia, insulin concentrations and lipid parameters in adult patients with overweight or obesity

Introduction

Hippocrates once said that “all disease begins in the gut,” and since the discovery of our gut microbiome, research has lent some preliminary credence to this lofty claim. Our gut, specifically the large intestine, is home to over 400 species of bacteria that outnumber our bodily cells. Contrary to the negative connotations of bacteria, our bacterial friends are thought to work synergistically with our digestive system to:

  • synthesize nutrients and enhance mineral absorption

  • produce antibacterial substances against pathogenic bacteria

  • suppress bacterial infections and enhance immune function

  • … and remove carcinogens

This raises an important question: If a healthy gut microbiome can offset disease, can people supplement the beneficial bacteria directly or promote their growth through prebiotic supplementation?

Who and what was studied?

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The big picture

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Other Articles in Issue #02 (December 2014)