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Study under review: Effect of Vitamin D Supplementation, Omega-3 Fatty Acid Supplementation, or a Strength-Training Exercise Program on Clinical Outcomes in Older Adults: The DO-HEALTH Randomized Clinical Trial
What was the question?
Is there any effect of vitamin D and omega-3 supplementation, or strength training alone or in combination, on blood pressure, nonvertebral bone fractures, physical performance, infection rate or cognition?
Why was the question worth asking?
How was the question answered?
What was the answer?
How much should you trust the answer?
What’s the take-home?
Other Articles in Issue #76 (February 2021)
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Safety spotlight: Sex, drugs, and weight loss supplements
We give the lowdown on a recent FDA crackdown on sexual enhancement and weight loss supplements.
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Interview: Lauren Bruzzone, PhD, JD
We chat with CrossFitter Lauren Bruzzone about how she's stayed fit throughout her life.
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Deep Dive: A heartbreaking story of EPA, DHA, and CVD
A major study looking at how pharmaceutical-grade fish oil affects CVD risk came up empty-handed. We cover that trial here and discuss its possible ramifications.
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Deep Dive: Cutting carbs may help reverse diabetes, but dietary adherence remains a challenge
Low-carb diets can reverse diabetes for some people, but they can be challenging to stick to, and longer-term efficacy remains uncertain.
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Curcumin reduces DOMS, with some caveats
A recent meta-analysis suggests a modest effect of curcumin on delayed-onset muscle soreness, but the quality of evidence ain't great.
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Deep Dive: Keto, carbs, and calories
A tightly-controlled experiment found that short-term keto led to more ad libitum food intake than a higher-carb diet, raising further doubts about the carbohydrate-insulin model of obesity.
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Deep Dive: Zinc and immunity
One big reason people take zinc is to boost immunity. This meta-analysis looked at the details of how supplementation impacted specific immune and inflammation markers.