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Study under review: Reduction in Saturated Fat Intake for Cardiovascular Disease
There has been substantial debate about whether or not saturated fat increases the risk of cardiovascular disease and, to date, there have been conflicting results from studies investigating this topic. For example, a 2010 meta-analysis of observational studies found that there was no association between saturated fat intake and cardiovascular disease. However, other observational studies have reported that there is an association. There has been some argument that even if there does not appear to be a clear association between saturated fat and cardiovascular disease, replacing saturated fat in the diet with risk-reducing nutrients may still reduce the overall risk for cardiovascular disease.
The present study was designed to systematically examine the impact of replacing saturated fat on all-cause mortality, cardiovascular mortality, and cardiovascular events in randomized controlled trials. Furthermore, the present study was designed to examine the effect of replacing saturated fat with carbohydrate, polyunsaturated, monounsaturated fat, and/or protein on the same outcomes.
The role of saturated fat in heart disease is still heavily debated in the pertinent literature. The present study was designed to examine data from randomized controlled trials on the effect of replacing saturated fat with carbohydrate, polyunsaturated, monounsaturated fat, and/or protein on mortality and cardiovascular morbidity.
Other Articles in Issue #70 (August 2020)
Mini: Chewing the (saturated) fat
Here are some takehomes from a recent debate exploring whether public health guidelines should push people to lower saturated fat intake as much as possible.
Green tea for weight loss: does it really work?
Betteridge's law of headlines doesn't hold here!
Tortoise and the hare: Comparing the effects of weight loss speed
This meta-analysis found that gradual weight loss led to better body composition outcomes, at least in the short term.
Deep Dive: What happens when you eat as much as possible?
Joey Chestnut may not have too much to worry about, but Nathan's should confirm these results by sponsoring a follow-up involving hot dogs, not pizza.
Safety Spotlight: Higher-dose vitamin D supplementation may weaken muscles in postmenopausal women
A 2018 study found that vitamin D supplementation weakened women's muscles. A recent follow-up explored why this may have happened.
Deep Dive: Subtle smarts from polyphenols for middle-aged adults
A recent meta-analysis suggests that polyphenols may impact some aspects of cognition in the short term. But that conclusion paints a picture with a really broad brush.
Mini: How much do nutrition professionals use the glycemic index?
A recent survey explored how much U.S. nutrition professionals use the glycemic index to educate their clients and patients. We summarize some of the key findings here.
Nulls: May-June 2020
The absence of evidence is sometimes evidence of absence!