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Deeper Dive: An inspirational approach to lowering blood pressure
Using a device to create resistance while inhaling could help lower the blood pressure of older adults with hypertension.
Deeper Dive: Another possible strike against the relationship between TMAO and heart disease
This secondary analysis of two trials found that TMAO levels go up even when consuming heart-healthy foods, raising questions about whether TMAO actually harms the heart.
Creatine dosing strategies for lean mass and strength gains in older adults
According to this meta-analysis, people over 50 who lift get a slight boost by supplementing creatine, with loading dosing and maybe pre-workout dosing providing better benefits.
Mini: Reliable associations between dietary factors and different kinds of cancer
In this Mini, we briefly describe the most reliable associations between dietary factors and cancers at various anatomical sites according to a recent umbrella review.
Deeper Dive: How do structural aspects of dietary carbohydrates determine glycemic response and appetite?
Starch structure seems to play a role in postprandial glycemic response but has no apparent impact on appetite hormones or satiety.
Beyond strict meal planning: dietary flexibility won’t hurt body composition goals
This study suggests that people looking to shed some fat for physique can do equally well with flexible and rigid diet plans.
Deeper Dive: Melatonin mysteries — can supplementation decrease circadian misalignment and body weight in night shift workers?
There was no apparent effect compared to placebo, but the study still hints at a positive impact.
Can beer hit the ‘pause’ button on menopause symptoms?
While this study found that beer could help with what ales people with menopausal symptoms, design and reporting issues hold this study back from being pitcher perfect.
Mini: When are lifestyle changes enough to treat high blood pressure and cholesterol?
We give a quick rundown of a recent scientific statement from the American Heart Association on the impact of lifestyle changes on blood pressure and cholesterol.
Citrulline malate may help you pump out a few extra reps
According to this meta-analysis, taking six to eight grams before a resistance training session could help crank out a few more reps. There was some evidence of publication bias, though.
Does exercise affect fat mass differently than a caloric deficit?
This review suggests that exercise alone can help people lose proportionally more visceral fat compared to dieting or dieting plus exercise. However, some nuances in how the study was analyzed make it difficult to put much faith in this finding.
Nulls: May–June 2021
Here's a quick roundup of studies that looked for evidence of efficacy but came up empty-handed.