<p>In this context, “vegetable” is a culinary term without a precise, widely-agreed-upon definition. While some definitions label all plant foods as vegetables,<a href="#ref-36" id="ref-link-36" class="ref-link popover" data-tooltip=""><sup>[36]</sup></a><a href="#ref-37" id="ref-link-37" class="ref-link popover" data-tooltip=""><sup>[37]</sup></a> others are more specific, excluding fruit, seeds, and nuts.<a href="#ref-36" id="ref-link-36" class="ref-link popover" data-tooltip=""><sup>[36]</sup></a><a href="#ref-38" id="ref-link-38" class="ref-link popover" data-tooltip=""><sup>[38]</sup></a> The most commonly-used definitions include potatoes.
Although potatoes are commonly considered vegetables, nutritionally they are more similar to starchy staple foods like bread, rice, and oats than to other foods we commonly call “vegetables”, like tomatoes, lettuce, and carrots. Most of the foods we call “vegetables” are low-calorie plant foods that have a high vitamin, mineral, and fiber content per calorie. For this reason, potatoes have sometimes been categorized differently than other vegetables in dietary guidelines<a href="#ref-39" id="ref-link-39" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;King JC, Slavin JL. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/23674809" target="\_blank" rel="noopener noreferrer"&gt;White potatoes, human health, and dietary guidance.&lt;/a&gt;&lt;/p&gt;Adv Nutr (2013-May-01)&lt;/div&gt;'><sup>[39]</sup></a> and scientific studies of diet-disease relationships.<a href="#ref-40" id="ref-link-40" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Monica L Bertoia, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/26394033" target="\_blank" rel="noopener noreferrer"&gt;Changes in Intake of Fruits and Vegetables and Weight Change in United States Men and Women Followed for Up to 24 Years: Analysis from Three Prospective Cohort Studies&lt;/a&gt;.&lt;/p&gt;PLoS Med (2015)&lt;/div&gt;'><sup>[40]</sup></a></p>

Are potatoes a vegetable?

<p>One medium potato with skin contains about 161 kilocalories, 88 percent of which is carbohydrate, 10 percent of which is protein, and 1 percent of which is fat.<a href="#ref-1" id="ref-link-1" class="ref-link popover" data-tooltip=""><sup>[1]</sup></a> Potatoes contain a broad array of vitamins and minerals but are particularly rich in potassium, manganese, vitamin C, and vitamin B6.<a href="#ref-1" id="ref-link-1" class="ref-link popover" data-tooltip=""><sup>[1]</sup></a> On a calorie-for-calorie basis, potatoes contain about as much fiber as whole grains — 3.8 grams per medium potato with skin.<a href="#ref-1" id="ref-link-1" class="ref-link popover" data-tooltip=""><sup>[1]</sup></a></p>
<div class="compact">
<div class="table-responsive"><table class="table table-bordered markdown-table caption-top">
                            <caption><p>Percent of daily value per 100 calories</p></caption><thead><tr><th class="text-center"></th><th class="text-center">Baked potato with skin</th><th class="text-center">Whole wheat bread</th><th class="text-center">White bread (enriched)</th></tr></thead><tbody><tr><td><div class="text-center">
Fiber
</div></td><td><div class="text-center">
9.4%
</div></td><td><div class="text-center">
10.9%
</div></td><td><div class="text-center">
3.8%
</div></td></tr><tr><td><div class="text-center">
Potassium
</div></td><td><div class="text-center">
16.5%
</div></td><td><div class="text-center">
2.8%
</div></td><td><div class="text-center">
1.1%
</div></td></tr><tr><td><div class="text-center">
Magnesium
</div></td><td><div class="text-center">
7.6%
</div></td><td><div class="text-center">
8.5%
</div></td><td><div class="text-center">
2.3%
</div></td></tr><tr><td><div class="text-center">
Calcium
</div></td><td><div class="text-center">
1.4%
</div></td><td><div class="text-center">
4.5%
</div></td><td><div class="text-center">
5.6%
</div></td></tr><tr><td><div class="text-center">
Iron
</div></td><td><div class="text-center">
6.5%
</div></td><td><div class="text-center">
5.3%
</div></td><td><div class="text-center">
7.9%
</div></td></tr><tr><td><div class="text-center">
Vitamin A
</div></td><td><div class="text-center">
0.4%
</div></td><td><div class="text-center">
0%
</div></td><td><div class="text-center">
0%
</div></td></tr><tr><td><div class="text-center">
Vitamin E
</div></td><td><div class="text-center">
0.4%
</div></td><td><div class="text-center">
1.2%
</div></td><td><div class="text-center">
0.4%
</div></td></tr><tr><td><div class="text-center">
Vitamin C
</div></td><td><div class="text-center">
17.3%
</div></td><td><div class="text-center">
0%
</div></td><td><div class="text-center">
0%
</div></td></tr></tbody>
                        </table></div>
</div>
<p>Among plant foods, potato protein stands out as being unusually complete and digestible.<a href="#ref-2" id="ref-link-2" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Steven R Hertzler, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/33266120" target="\_blank" rel="noopener noreferrer"&gt;Plant Proteins: Assessing Their Nutritional Quality and Effects on Health and Physical Function&lt;/a&gt;.&lt;/p&gt;Nutrients (2020)&lt;/div&gt;'><sup>[2]</sup></a> In other words, it has an amino acid profile similar to what the human body needs to maintain itself and build muscle, while most plant foods have to be combined with other plant or animal foods to achieve this. However, the total amount of protein in potatoes is modest at 4.3 grams per medium spud.<a href="#ref-1" id="ref-link-1" class="ref-link popover" data-tooltip=""><sup>[1]</sup></a></p>
<p>Potatoes contain a significant amount of non-essential phytochemicals. These include polyphenols, especially phenolic acids (also found in coffee) and, in purple potatoes specifically, anthocyanins (also found in blueberries),<a href="#ref-3" id="ref-link-3" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Akyol H, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/27240356" target="\_blank" rel="noopener noreferrer"&gt;Phenolic Compounds in the Potato and Its Byproducts: An Overview.&lt;/a&gt;&lt;/p&gt;Int J Mol Sci (2016-May-27)&lt;/div&gt;'><sup>[3]</sup></a> which are most concentrated in the skin but also present in the flesh.<a href="#ref-3" id="ref-link-3" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Akyol H, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/27240356" target="\_blank" rel="noopener noreferrer"&gt;Phenolic Compounds in the Potato and Its Byproducts: An Overview.&lt;/a&gt;&lt;/p&gt;Int J Mol Sci (2016-May-27)&lt;/div&gt;'><sup>[3]</sup></a> Observational research suggests that foods high in polyphenols, including anthocyanins, may reduce the risk of cardiovascular disease and type 2 diabetes<a href="#ref-4" id="ref-link-4" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Rienks J, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/29931039" target="\_blank" rel="noopener noreferrer"&gt;Polyphenol exposure and risk of type 2 diabetes: dose-response meta-analyses and systematic review of prospective cohort studies.&lt;/a&gt;&lt;/p&gt;Am J Clin Nutr (2018-Jul-01)&lt;/div&gt;'><sup>[4]</sup></a><a href="#ref-5" id="ref-link-5" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Cassidy A, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/23319811" target="\_blank" rel="noopener noreferrer"&gt;High anthocyanin intake is associated with a reduced risk of myocardial infarction in young and middle-aged women.&lt;/a&gt;&lt;/p&gt;Circulation (2013-Jan-15)&lt;/div&gt;'><sup>[5]</sup></a>.</p>
<p>Randomized controlled trials report that these polyphenols found in potatoes reduce blood pressure and improve endothelial function, consistent with the idea that they may lower cardiovascular disease risk.<a href="#ref-6" id="ref-link-6" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Onakpoya IJ, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/24943289" target="\_blank" rel="noopener noreferrer"&gt;The effect of chlorogenic acid on blood pressure: a systematic review and meta-analysis of randomized clinical trials.&lt;/a&gt;&lt;/p&gt;J Hum Hypertens (2015-Feb)&lt;/div&gt;'><sup>[6]</sup></a><a href="#ref-7" id="ref-link-7" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Fairlie-Jones L, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/28825651" target="\_blank" rel="noopener noreferrer"&gt;The Effect of Anthocyanin-Rich Foods or Extracts on Vascular Function in Adults: A Systematic Review and Meta-Analysis of Randomised Controlled Trials&lt;/a&gt;.&lt;/p&gt;Nutrients (2017)&lt;/div&gt;'><sup>[7]</sup></a> However, there is no direct evidence that consuming potatoes prevents cardiovascular events. </p>
<p>Yellow-fleshed potatoes can also contain a significant amount of carotenoids, especially <a href="/supplements/lutein/" class="popover" data-tooltip="&lt;div&gt;&lt;h6&gt;Lutein&lt;/h6&gt;&lt;p&gt;Lutein, as well as the related zeaxanthin, are carotenoid structures similar to pre-vitamin A (β-carotene) and involved in eye health. A dietary component of eggs, lutein appears to be effective for this claim and a general antioxidant.&lt;/p&gt;&lt;/div&gt;">lutein</a> (also found in green vegetables like spinach).<a href="#ref-8" id="ref-link-8" class="ref-link popover" data-tooltip=""><sup>[8]</sup></a> Lutein plays a role in preventing and slowing the progression of <a href="/conditions/macular-degeneration/" class="popover" data-tooltip="&lt;div&gt;&lt;h6&gt;Macular Degeneration&lt;/h6&gt;&lt;p&gt;Macular degeneration (aka age-related macular degeneration) is a condition that causes blurred, limited, or no vision in the center of the eye’s visual field.&lt;/p&gt;&lt;/div&gt;">macular degeneration</a>, a common cause of visual impairment in the elderly.<a href="#ref-9" id="ref-link-9" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Liwen Feng, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/31887124" target="\_blank" rel="noopener noreferrer"&gt;Effects of lutein supplementation in age-related macular degeneration&lt;/a&gt;.&lt;/p&gt;PLoS One (2019)&lt;/div&gt;'><sup>[9]</sup></a></p>

Which nutrients and other compounds are in potatoes?

<p>White potatoes (Solanum tuberosum) and sweet potatoes (Ipomoea batatas) are both nutritious foods and we have not identified studies directly comparing their impacts on health.
White potatoes and sweet potatoes have a similar calorie density and carbohydrate content. White potatoes have a bit more protein, while sweet potatoes have a bit more fiber. Sweet potatoes contain more of several vitamins and minerals, including vitamin A precursors, vitamin C, and calcium, while white potatoes contain more folate.<a href="#ref-1" id="ref-link-1" class="ref-link popover" data-tooltip=""><sup>[1]</sup></a><a href="#ref-41" id="ref-link-41" class="ref-link popover" data-tooltip=""><sup>[41]</sup></a></p>
<p>White potatoes and sweet potatoes both tend to have a high glycemic index, but the glycemic index of white potatoes is typically somewhat higher.<a href="#ref-17" id="ref-link-17" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Atkinson FS, Foster-Powell K, Brand-Miller JC. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/18835944" target="\_blank" rel="noopener noreferrer"&gt;International tables of glycemic index and glycemic load values: 2008&lt;/a&gt;.&lt;/p&gt;Diabetes Care (2008)&lt;/div&gt;'><sup>[17]</sup></a></p>

Are white potatoes less healthy than sweet potatoes?

<p>Potatoes are one of the richest dietary sources of potassium, an important mineral for keeping blood pressure within a healthy range and preventing cardiovascular events like heart attack and stroke.<a href="#ref-10" id="ref-link-10" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Jalal Poorolajal, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/28419159" target="\_blank" rel="noopener noreferrer"&gt;Oral potassium supplementation for management of essential hypertension: A meta-analysis of randomized controlled trials&lt;/a&gt;.&lt;/p&gt;PLoS One (2017)&lt;/div&gt;'><sup>[10]</sup></a><a href="#ref-11" id="ref-link-11" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Bruce Neal, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/34459569" target="\_blank" rel="noopener noreferrer"&gt;Effect of Salt Substitution on Cardiovascular Events and Death&lt;/a&gt;.&lt;/p&gt;N Engl J Med (2021)&lt;/div&gt;'><sup>[11]</sup></a> A commonly-used dose in studies that report blood pressure reductions from potassium supplementation is 2.3 grams per day, approximately the amount in two medium potatoes.<a href="#ref-10" id="ref-link-10" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Jalal Poorolajal, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/28419159" target="\_blank" rel="noopener noreferrer"&gt;Oral potassium supplementation for management of essential hypertension: A meta-analysis of randomized controlled trials&lt;/a&gt;.&lt;/p&gt;PLoS One (2017)&lt;/div&gt;'><sup>[10]</sup></a><a href="#ref-1" id="ref-link-1" class="ref-link popover" data-tooltip=""><sup>[1]</sup></a></p>
<p>One randomized controlled crossover trial compared the impact of non-fried potatoes, fried potatoes, potassium supplements, and usual diet on blood pressure over 17-day diet periods in people with high blood pressure.<a href="#ref-12" id="ref-link-12" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Michael S Stone, Berdine R Martin, Connie M Weaver. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/34064968" target="\_blank" rel="noopener noreferrer"&gt;Short-Term RCT of Increased Dietary Potassium from Potato or Potassium Gluconate: Effect on Blood Pressure, Microcirculation, and Potassium and Sodium Retention in Pre-Hypertensive-to-Hypertensive Adults&lt;/a&gt;.&lt;/p&gt;Nutrients (2021)&lt;/div&gt;'><sup>[12]</sup></a> Systolic blood pressure tended to be lower on the non-fried potato diet vs. usual diet, but this didn’t reach statistical significance. In contrast, the decline in systolic blood pressure from baseline was significantly greater for the non-fried potato group vs. usual diet, but this was a secondary outcome. The decline in blood pressure did not reach statistical significance on the diet with fried potatoes or potassium supplements.</p>
<p>An additional small trial reports that eating eight small purple potatoes per day for four weeks reduces blood pressure in people with high blood pressure (hypertension), but the finding should be interpreted with caution due to major methodological weaknesses.<a href="#ref-13" id="ref-link-13" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Vinson JA, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/22224463" target="\_blank" rel="noopener noreferrer"&gt;High-antioxidant potatoes: acute in vivo antioxidant source and hypotensive agent in humans after supplementation to hypertensive subjects.&lt;/a&gt;&lt;/p&gt;J Agric Food Chem (2012-Jul-11)&lt;/div&gt;'><sup>[13]</sup></a> For example, the paper doesn’t statistically compare blood pressure in the intervention group against the control group, which is the most important comparison in a controlled trial. Together, these two randomized controlled trials provide modest evidence that eating non-fried potatoes can lower blood pressure, consistent with the high potassium content of spuds.</p>
<p>In a study testing the satiety (fullness after a meal) effects of 32 commonly-eaten foods, boiled potatoes were the most sating per calorie, beating other high-satiety foods like fish, steak, fruit, and oatmeal.<a href="#ref-14" id="ref-link-14" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Holt SH, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/7498104" target="\_blank" rel="noopener noreferrer"&gt;A satiety index of common foods&lt;/a&gt;.&lt;/p&gt;Eur J Clin Nutr (1995)&lt;/div&gt;'><sup>[14]</sup></a> Baked potatoes are expected to be comparable due to their similar composition and palatability. This suggests that potatoes may be helpful for controlling calorie intake and body weight, although this hasn’t been directly tested. It’s also important to note that this study used plain potatoes, and the effects would likely be different with added butter, cheese or other calorie-dense toppings.</p>
<p>Potatoes are unusually nutritionally complete. Although a potato-only diet lacks significant quantities of vitamins A, E, and B12, most other essential nutrients are present at adequate or near-adequate levels. Small experiments in the early 20th century reported that people can eat almost nothing but potatoes for 5.5 to 10 months with no apparent ill effects.<a href="#ref-15" id="ref-link-15" class="ref-link popover" data-tooltip=""><sup>[15]</sup></a><a href="#ref-16" id="ref-link-16" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Kon SK, Klein A. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/16744005" target="\_blank" rel="noopener noreferrer"&gt;The value of whole potato in human nutrition.&lt;/a&gt;&lt;/p&gt;Biochem J (1928)&lt;/div&gt;'><sup>[16]</sup></a></p>

What are the main benefits of potatoes?

<p>Most, but not all varieties of potatoes have a high glycemic index.<a href="#ref-42" id="ref-link-42" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Ek KL, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/24103358" target="\_blank" rel="noopener noreferrer"&gt;Discovery of a low-glycaemic index potato and relationship with starch digestion in vitro.&lt;/a&gt;&lt;/p&gt;Br J Nutr (2014-Feb)&lt;/div&gt;'><sup>[42]</sup></a><a href="#ref-17" id="ref-link-17" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Atkinson FS, Foster-Powell K, Brand-Miller JC. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/18835944" target="\_blank" rel="noopener noreferrer"&gt;International tables of glycemic index and glycemic load values: 2008&lt;/a&gt;.&lt;/p&gt;Diabetes Care (2008)&lt;/div&gt;'><sup>[17]</sup></a><a href="#ref-43" id="ref-link-43" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Henry CJ, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/16351768" target="\_blank" rel="noopener noreferrer"&gt;Glycaemic index values for commercially available potatoes in Great Britain.&lt;/a&gt;&lt;/p&gt;Br J Nutr (2005-Dec)&lt;/div&gt;'><sup>[43]</sup></a> For example, the varieties ‘Carisma’ and ‘Nicola’ have a low and medium glycemic index, respectively.<a href="#ref-42" id="ref-link-42" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Ek KL, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/24103358" target="\_blank" rel="noopener noreferrer"&gt;Discovery of a low-glycaemic index potato and relationship with starch digestion in vitro.&lt;/a&gt;&lt;/p&gt;Br J Nutr (2014-Feb)&lt;/div&gt;'><sup>[42]</sup></a> Frying or cooling potatoes after cooking typically reduces their glycemic index.<a href="#ref-17" id="ref-link-17" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Atkinson FS, Foster-Powell K, Brand-Miller JC. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/18835944" target="\_blank" rel="noopener noreferrer"&gt;International tables of glycemic index and glycemic load values: 2008&lt;/a&gt;.&lt;/p&gt;Diabetes Care (2008)&lt;/div&gt;'><sup>[17]</sup></a> Yet don’t count on frying potatoes to improve their healthfulness, as fried potatoes are less filling per calorie,<a href="#ref-14" id="ref-link-14" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Holt SH, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/7498104" target="\_blank" rel="noopener noreferrer"&gt;A satiety index of common foods&lt;/a&gt;.&lt;/p&gt;Eur J Clin Nutr (1995)&lt;/div&gt;'><sup>[14]</sup></a> associated with weight gain,<a href="#ref-31" id="ref-link-31" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Dariush Mozaffarian, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/21696306" target="\_blank" rel="noopener noreferrer"&gt;Changes in diet and lifestyle and long-term weight gain in women and men&lt;/a&gt;.&lt;/p&gt;N Engl J Med (2011)&lt;/div&gt;'><sup>[31]</sup></a> and associated with a higher risk of developing diabetes and cardiovascular disease.<a href="#ref-26" id="ref-link-26" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Schwingshackl L, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/29987352" target="\_blank" rel="noopener noreferrer"&gt;Potatoes and risk of chronic disease: a systematic review and dose-response meta-analysis.&lt;/a&gt;&lt;/p&gt;Eur J Nutr (2019-Sep)&lt;/div&gt;'><sup>[26]</sup></a><a href="#ref-27" id="ref-link-27" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Isao Muraki, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/26681722" target="\_blank" rel="noopener noreferrer"&gt;Potato Consumption and Risk of Type 2 Diabetes: Results From Three Prospective Cohort Studies&lt;/a&gt;.&lt;/p&gt;Diabetes Care (2016)&lt;/div&gt;'><sup>[27]</sup></a></p>

Do all potatoes have a high glycemic index?

<p>Some people believe plants in the nightshade family cause inflammation, joint pain, digestive discomfort, and other problems. Potatoes can cause digestive distress, especially if they are green, damaged, or sprouting, but there is scant evidence that they cause inflammation or joint pain.</p>
<p>One randomized controlled trial tested the impact of potatoes on markers of inflammation, reporting that a single meal of potatoes led to higher circulating levels of the inflammatory cytokine <a href="/outcomes/interleukin-6/" class="popover" data-tooltip="&lt;div&gt;&lt;h6&gt;Interleukin 6&lt;/h6&gt;&lt;p&gt;Interleukin 6 (IL-6) is a proinflammatory cytokine that is thought to reflect a more inflammatory state in the body.&lt;/p&gt;&lt;/div&gt;">interleukin-6</a> in lean women but not women with obesity, and higher circulating levels of the inflammatory cytokine <em><a href="/outcomes/tnf-alpha/" class="popover" data-tooltip="&lt;div&gt;&lt;h6&gt;TNF-Alpha&lt;/h6&gt;&lt;p&gt;Tumor necrosis factor alpha (TNF-α) is a proinflammatory cytokine that is used as a marker of inflammation. Its reduction is thought to reflect a lesser state of inflammation in the body.&lt;/p&gt;&lt;/div&gt;">tumor necrosis factor-alpha</a></em> (TNF-⍺) in women with obesity but not lean women, relative to All-Bran cereal in the six hours following the meal.<a href="#ref-44" id="ref-link-44" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Manning PJ, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/19186329" target="\_blank" rel="noopener noreferrer"&gt;Postprandial cytokine concentrations and meal composition in obese and lean women.&lt;/a&gt;&lt;/p&gt;Obesity (Silver Spring) (2008-Sep)&lt;/div&gt;'><sup>[44]</sup></a> This result should be viewed with caution since the study reports many outcomes without statistically correcting for multiple comparisons, increasing the probability that some of the findings are due to chance. It is also not clear how potatoes would have fared if they had been compared to other types of food. A 4-week randomized controlled trial, meanwhile, found potatoes and refined grains did not clearly differ in their effect on the inflammatory marker <em><a href="/outcomes/c-reactive-protein/" class="popover" data-tooltip="&lt;div&gt;&lt;h6&gt;C-Reactive Protein (CRP)&lt;/h6&gt;&lt;p&gt;C-Reactive protein is an inflammatory biomarker for cardiovascular disease and atherosclerosis (arterial plaque). Its reduction is thought to be protective and reduces the risk of cardiovascular incidents.&lt;/p&gt;&lt;/div&gt;">C-reactive protein</a> (CRP).</em></p>
<p>Randomized controlled trials tend to suggest that eating tomatoes or tomato extracts, another food in the nightshade family, reduce markers of inflammation, although not all findings have been consistent.<a href="#ref-45" id="ref-link-45" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Ghavipour M, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/23069270" target="\_blank" rel="noopener noreferrer"&gt;Tomato juice consumption reduces systemic inflammation in overweight and obese females.&lt;/a&gt;&lt;/p&gt;Br J Nutr (2013-Jun)&lt;/div&gt;'><sup>[45]</sup></a><a href="#ref-46" id="ref-link-46" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Burton-Freeman B, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/22331646" target="\_blank" rel="noopener noreferrer"&gt;Protective activity of processed tomato products on postprandial oxidation and inflammation: a clinical trial in healthy weight men and women.&lt;/a&gt;&lt;/p&gt;Mol Nutr Food Res (2012-Apr)&lt;/div&gt;'><sup>[46]</sup></a><a href="#ref-47" id="ref-link-47" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Groten K, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/30836363" target="\_blank" rel="noopener noreferrer"&gt;Tomato Phytonutrients Balance UV Response: Results from a Double-Blind, Randomized, Placebo-Controlled Study.&lt;/a&gt;&lt;/p&gt;Skin Pharmacol Physiol (2019)&lt;/div&gt;'><sup>[47]</sup></a><a href="#ref-48" id="ref-link-48" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Riso P, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/16569044" target="\_blank" rel="noopener noreferrer"&gt;Effect of a tomato-based drink on markers of inflammation, immunomodulation, and oxidative stress.&lt;/a&gt;&lt;/p&gt;J Agric Food Chem (2006-Apr-05)&lt;/div&gt;'><sup>[48]</sup></a><a href="#ref-49" id="ref-link-49" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Blum A, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/17716544" target="\_blank" rel="noopener noreferrer"&gt;Tomato-rich (Mediterranean) diet does not modify inflammatory markers.&lt;/a&gt;&lt;/p&gt;Clin Invest Med (2007)&lt;/div&gt;'><sup>[49]</sup></a></p>
<p>Nightshades, including potatoes, contain glycoalkaloids, which can cause digestive distress. These are only present in potentially dangerous amounts in potatoes that are green, damaged, diseased, and potato sprouts. Peeling potatoes removes most of their glycoalkaloid content.<a href="#ref-30" id="ref-link-30" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Friedman M. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/17090106" target="\_blank" rel="noopener noreferrer"&gt;Potato glycoalkaloids and metabolites: roles in the plant and in the diet.&lt;/a&gt;&lt;/p&gt;J Agric Food Chem (2006-Nov-15)&lt;/div&gt;'><sup>[30]</sup></a></p>

Are potatoes harmful because they’re nightshades?

<p>Most types of potatoes, such as the common russet, have a high glycemic index. This means they increase blood glucose more than most other foods containing the same amount of carbohydrate. However, this varies by potato type and processing method. For example, frying potatoes, or cooling them after cooking, tends to lower their glycemic index.<a href="#ref-17" id="ref-link-17" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Atkinson FS, Foster-Powell K, Brand-Miller JC. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/18835944" target="\_blank" rel="noopener noreferrer"&gt;International tables of glycemic index and glycemic load values: 2008&lt;/a&gt;.&lt;/p&gt;Diabetes Care (2008)&lt;/div&gt;'><sup>[17]</sup></a> Potatoes also have a high insulin index, meaning they increase insulin secretion more than most other foods.<a href="#ref-18" id="ref-link-18" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Holt SH, Miller JC, Petocz P. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/9356547" target="\_blank" rel="noopener noreferrer"&gt;An insulin index of foods: the insulin demand generated by 1000-kJ portions of common foods&lt;/a&gt;.&lt;/p&gt;Am J Clin Nutr (1997)&lt;/div&gt;'><sup>[18]</sup></a> The health implications of this aren’t entirely clear. Observational studies report no consistent association between the habitual glycemic index of the diet and body mass index, a measure of body fatness. Similarly, randomized controlled trials report no consistent effect of glycemic index on body weight.<a href="#ref-19" id="ref-link-19" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Glenn A Gaesser, Julie Miller Jones, Siddhartha S Angadi. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/34352885" target="\_blank" rel="noopener noreferrer"&gt;Perspective: Does Glycemic Index Matter for Weight Loss and Obesity Prevention? Examination of the Evidence on "Fast" Compared with "Slow" Carbs&lt;/a&gt;.&lt;/p&gt;Adv Nutr (2021)&lt;/div&gt;'><sup>[19]</sup></a> In contrast, observational studies report that diets higher in glycemic index tend to be associated with a higher risk of developing type 2 diabetes,<a href="#ref-20" id="ref-link-20" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Darren C Greenwood, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/24265366" target="\_blank" rel="noopener noreferrer"&gt;Glycemic index, glycemic load, carbohydrates, and type 2 diabetes: systematic review and dose-response meta-analysis of prospective studies&lt;/a&gt;.&lt;/p&gt;Diabetes Care (2013)&lt;/div&gt;'><sup>[20]</sup></a><a href="#ref-21" id="ref-link-21" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Bhupathiraju SN, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/24787496" target="\_blank" rel="noopener noreferrer"&gt;Glycemic index, glycemic load, and risk of type 2 diabetes: results from 3 large US cohorts and an updated meta-analysis&lt;/a&gt;.&lt;/p&gt;Am J Clin Nutr (2014)&lt;/div&gt;'><sup>[21]</sup></a> and a higher risk of cardiovascular disease in women but not men.<a href="#ref-22" id="ref-link-22" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Fan J, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/23284926" target="\_blank" rel="noopener noreferrer"&gt;Dietary glycemic index, glycemic load, and risk of coronary heart disease, stroke, and stroke mortality: a systematic review with meta-analysis.&lt;/a&gt;&lt;/p&gt;PLoS One (2012)&lt;/div&gt;'><sup>[22]</sup></a><a href="#ref-23" id="ref-link-23" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Dong JY, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/22440121" target="\_blank" rel="noopener noreferrer"&gt;Meta-analysis of dietary glycemic load and glycemic index in relation to risk of coronary heart disease.&lt;/a&gt;&lt;/p&gt;Am J Cardiol (2012-Jun-01)&lt;/div&gt;'><sup>[23]</sup></a><a href="#ref-24" id="ref-link-24" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Mirrahimi A, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/23316283" target="\_blank" rel="noopener noreferrer"&gt;Associations of glycemic index and load with coronary heart disease events: a systematic review and meta-analysis of prospective cohorts.&lt;/a&gt;&lt;/p&gt;J Am Heart Assoc (2012-Oct)&lt;/div&gt;'><sup>[24]</sup></a> In addition, people with diabetes may have a harder time controlling their blood sugar levels when they eat high-glycemic foods.<a href="#ref-25" id="ref-link-25" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Mohammad Ishraq Zafar, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/31374573" target="\_blank" rel="noopener noreferrer"&gt;Low-glycemic index diets as an intervention for diabetes: a systematic review and meta-analysis&lt;/a&gt;.&lt;/p&gt;Am J Clin Nutr (2019)&lt;/div&gt;'><sup>[25]</sup></a> </p>
<p>When considering potatoes specifically, there is no consistent association between the intake of boiled, baked, or mashed potatoes and cardiovascular risk in observational studies, but they are correlated with a slightly higher risk of type 2 diabetes. Intake of fried potatoes is more strongly associated with the risk of cardiovascular disease and type 2 diabetes in these studies, despite the lower glycemic index of fried potatoes.<a href="#ref-26" id="ref-link-26" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Schwingshackl L, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/29987352" target="\_blank" rel="noopener noreferrer"&gt;Potatoes and risk of chronic disease: a systematic review and dose-response meta-analysis.&lt;/a&gt;&lt;/p&gt;Eur J Nutr (2019-Sep)&lt;/div&gt;'><sup>[26]</sup></a><a href="#ref-27" id="ref-link-27" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Isao Muraki, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/26681722" target="\_blank" rel="noopener noreferrer"&gt;Potato Consumption and Risk of Type 2 Diabetes: Results From Three Prospective Cohort Studies&lt;/a&gt;.&lt;/p&gt;Diabetes Care (2016)&lt;/div&gt;'><sup>[27]</sup></a></p>
<p>Potatoes contain oxalates, which can contribute to the formation of kidney stones in susceptible people.<a href="#ref-28" id="ref-link-28" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Noonan SC, Savage GP. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/24393738" target="\_blank" rel="noopener noreferrer"&gt;Oxalate content of foods and its effect on humans.&lt;/a&gt;&lt;/p&gt;Asia Pac J Clin Nutr (1999-Mar)&lt;/div&gt;'><sup>[28]</sup></a><a href="#ref-29" id="ref-link-29" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Mitchell T, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/30566003" target="\_blank" rel="noopener noreferrer"&gt;Dietary oxalate and kidney stone formation.&lt;/a&gt;&lt;/p&gt;Am J Physiol Renal Physiol (2019-Mar-01)&lt;/div&gt;'><sup>[29]</sup></a></p>
<p>Potatoes also contain the toxic glycoalkaloids solanine and chaconine, which can cause digestive distress and in very rare cases can be fatal. These are only present in potentially dangerous amounts in potatoes that are green, damaged, diseased, and potato sprouts. Peeling potatoes removes most of their glycoalkaloid content.<a href="#ref-30" id="ref-link-30" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Friedman M. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/17090106" target="\_blank" rel="noopener noreferrer"&gt;Potato glycoalkaloids and metabolites: roles in the plant and in the diet.&lt;/a&gt;&lt;/p&gt;J Agric Food Chem (2006-Nov-15)&lt;/div&gt;'><sup>[30]</sup></a></p>
<p>Per calorie, potatoes are not as dense in vitamins and minerals as low-calorie vegetables like greens, broccoli, and carrots. This isn’t necessarily a problem if potatoes are eaten as a starch alongside vegetables, as one would eat rice or bread. But if they’re viewed as a vegetable and eaten instead of low-calorie vegetables, they may lead to a lower intake of vitamins and minerals and a higher calorie intake.</p>

What are the main drawbacks of potatoes?

<p>Potatoes should be stored in a cool, dark place, but ideally not the refrigerator.<a href="#ref-50" id="ref-link-50" class="ref-link popover" data-tooltip=""><sup>[50]</sup></a>.</p>
<ul>
<li>The most important guideline is to store potatoes in the dark. When exposed to light, potatoes produce higher levels of toxic glycoalkaloids in the skin and just below it. Although glycoalkaloids are not visible, the potato’s skin also turns green when exposed to light, and the green color is visible.</li>
<li>Storing potatoes in a cool place is not necessary but it prolongs their storage life.</li>
<li>Storing potatoes in the refrigerator (less than 40 degrees F) for a week or more causes them to sweeten, which some people may not like. They are, however, safe to eat.</li>
</ul>

How should potatoes be stored?

<p>Potatoes are commonly eaten baked, boiled, mashed, and fried. Relative to the other three preparation methods, frying results in a lower glycemic index, higher calorie density, greater  palatability, and lower satiety per calorie.<a href="#ref-17" id="ref-link-17" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Atkinson FS, Foster-Powell K, Brand-Miller JC. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/18835944" target="\_blank" rel="noopener noreferrer"&gt;International tables of glycemic index and glycemic load values: 2008&lt;/a&gt;.&lt;/p&gt;Diabetes Care (2008)&lt;/div&gt;'><sup>[17]</sup></a><a href="#ref-14" id="ref-link-14" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Holt SH, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/7498104" target="\_blank" rel="noopener noreferrer"&gt;A satiety index of common foods&lt;/a&gt;.&lt;/p&gt;Eur J Clin Nutr (1995)&lt;/div&gt;'><sup>[14]</sup></a> This is likely to increase calorie intake and contribute to weight gain. Consistent with this, an observational study reported that people who increase their intake of French fries and potato chips experienced much more weight gain than people who increased their intake of baked, boiled, or mashed potatoes.<a href="#ref-31" id="ref-link-31" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Dariush Mozaffarian, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/21696306" target="\_blank" rel="noopener noreferrer"&gt;Changes in diet and lifestyle and long-term weight gain in women and men&lt;/a&gt;.&lt;/p&gt;N Engl J Med (2011)&lt;/div&gt;'><sup>[31]</sup></a> This must be interpreted with some caution due to the possibility of confounding by other diet and lifestyle factors. Adding calorie-dense toppings or ingredients like butter and cheese to baked, boiled, and mashed potatoes is expected to make them less filling per calorie.</p>
<p>Cooling potatoes after cooking tends to reduce their glycemic index and insulin index, even if they are subsequently reheated, although this is not always the case.<a href="#ref-32" id="ref-link-32" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Patterson MA, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/31484331" target="\_blank" rel="noopener noreferrer"&gt;Chilled Potatoes Decrease Postprandial Glucose, Insulin, and Glucose-dependent Insulinotropic Peptide Compared to Boiled Potatoes in Females with Elevated Fasting Glucose and Insulin.&lt;/a&gt;&lt;/p&gt;Nutrients (2019-Sep-03)&lt;/div&gt;'><sup>[32]</sup></a><a href="#ref-33" id="ref-link-33" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Fernandes G, Velangi A, Wolever TM. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/15800557" target="\_blank" rel="noopener noreferrer"&gt;Glycemic index of potatoes commonly consumed in North America.&lt;/a&gt;&lt;/p&gt;J Am Diet Assoc (2005-Apr)&lt;/div&gt;'><sup>[33]</sup></a> To the extent that dietary glycemic index and insulin index may impact health, cooling potatoes prior to eating may make them healthier.</p>
<p>High-temperature cooking of some foods creates a carcinogen called acrylamide, and fried potatoes are one of the largest dietary exposures to this compound.<a href="#ref-34" id="ref-link-34" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Raffan S, Halford NG. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/31866690" target="\_blank" rel="noopener noreferrer"&gt;Acrylamide in food: Progress in and prospects for genetic and agronomic solutions.&lt;/a&gt;&lt;/p&gt;Ann Appl Biol (2019-Nov)&lt;/div&gt;'><sup>[34]</sup></a> Although dietary acrylamide is a theoretical concern, observational studies have not reported consistent links between dietary acrylamide intake and the risk of cancer at any site, with the possible exception of kidney cancer.<a href="#ref-35" id="ref-link-35" class="ref-link popover" data-tooltip='&lt;div&gt;&lt;p class="mb-3"&gt;Pelucchi C, et al. &lt;a href="https://pubmed.ncbi.nlm.nih.gov/25403648" target="\_blank" rel="noopener noreferrer"&gt;Dietary acrylamide and cancer risk: an updated meta-analysis&lt;/a&gt;.&lt;/p&gt;Int J Cancer (2015)&lt;/div&gt;'><sup>[35]</sup></a> Soaking potatoes prior to frying reduces the formation of acrylamide.</p>

How does preparation method impact the healthfulness of potatoes?

Potatoes

Other

Morgan Pfiffner

<p>Potatoes</p>
<div class="compact">
<div class="table-responsive"><table class="table table-bordered markdown-table caption-top">
                            <caption><p>Percent of daily value per 100 calories</p></caption><thead><tr><th class="text-center"></th><th class="text-center">Baked potato with skin</th><th class="text-center">Whole wheat bread</th><th class="text-center">White bread (enriched)</th></tr></thead><tbody><tr><td><div class="text-center">
Fiber
</div></td><td><div class="text-center">
9.4%
</div></td><td><div class="text-center">
10.9%
</div></td><td><div class="text-center">
3.8%
</div></td></tr><tr><td><div class="text-center">
Potassium
</div></td><td><div class="text-center">
16.5%
</div></td><td><div class="text-center">
2.8%
</div></td><td><div class="text-center">
1.1%
</div></td></tr><tr><td><div class="text-center">
Magnesium
</div></td><td><div class="text-center">
7.6%
</div></td><td><div class="text-center">
8.5%
</div></td><td><div class="text-center">
2.3%
</div></td></tr><tr><td><div class="text-center">
Calcium
</div></td><td><div class="text-center">
1.4%
</div></td><td><div class="text-center">
4.5%
</div></td><td><div class="text-center">
5.6%
</div></td></tr><tr><td><div class="text-center">
Iron
</div></td><td><div class="text-center">
6.5%
</div></td><td><div class="text-center">
5.3%
</div></td><td><div class="text-center">
7.9%
</div></td></tr><tr><td><div class="text-center">
Vitamin A
</div></td><td><div class="text-center">
0.4%
</div></td><td><div class="text-center">
0%
</div></td><td><div class="text-center">
0%
</div></td></tr><tr><td><div class="text-center">
Vitamin E
</div></td><td><div class="text-center">
0.4%
</div></td><td><div class="text-center">
1.2%
</div></td><td><div class="text-center">
0.4%
</div></td></tr><tr><td><div class="text-center">
Vitamin C
</div></td><td><div class="text-center">
17.3%
</div></td><td><div class="text-center">
0%
</div></td><td><div class="text-center">
0%
</div></td></tr></tbody>
                        </table></div>
</div>