Very low density cholesterol (vLDL-C) is the lipoprotein synthesized in the liver, and is able to convert to LDL-C when in circulation.

This page features 3 unique references to scientific papers.

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The Human Effect Matrix looks at human studies (excluding animal/petri-dish studies) to tell you what supplements affect vLDL-C
Grade Level of Evidence
A Robust research conducted with repeated double blind clinical trials
B Multiple studies where at least two are double-blind and placebo controlled
C Single double blind study or multiple cohort studies
D Uncontrolled or observational studies only
Level of Evidence
Magnitude of Effect Size
Scientific Consensus Comments
B Fish Oil
Comparative Health Goals evidence only available to buyers of our Supplement-Goals Reference

All information is still available and viewable on their respective supplement page.
B Chromium
C Vitamin B3
C Shilajit
C Biotin
C Cocoa Extract
C Creatine
C Guggul
C Quercetin
D Eclipta alba


  1. Colombo VE1, et al Treatment of brittle fingernails and onychoschizia with biotin: scanning electron microscopy . J Am Acad Dermatol. (1990)
  2. Revilla-Monsalve C1, et al Biotin supplementation reduces plasma triacylglycerol and VLDL in type 2 diabetic patients and in nondiabetic subjects with hypertriglyceridemia . Biomed Pharmacother. (2006)
  3. Marshall MW, et al Effects of biotin on lipids and other constituents of plasma of healthy men and women . Artery. (1980)

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