Very low density cholesterol (vLDL-C) is the lipoprotein synthesized in the liver, and is able to convert to LDL-C when in circulation.

This page features 12 unique references to scientific papers.

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The Human Effect Matrix looks at human studies (excluding animal/petri-dish studies) to tell you what supplements affect vLDL-C
Grade Level of Evidence
A Robust research conducted with repeated double blind clinical trials
B Multiple studies where at least two are double-blind and placebo controlled
C Single double blind study or multiple cohort studies
D Uncontrolled or observational studies only
Level of Evidence
Magnitude of Effect Size
Scientific Consensus Comments
B Fish Oil
Comparative Health Goals evidence only available to buyers of our Supplement-Goals Reference

All information is still available and viewable on their respective supplement page.
B Chromium
C Vitamin B3
C Shilajit
C Biotin
C Cocoa Extract
C Creatine
C Guggul
C Quercetin
D Eclipta alba


  1. Dietary anti-oxidant supplementation combined with Quercetin improves cycling time trial performance
  2. MacRae HS, Mefferd KM Dietary antioxidant supplementation combined with quercetin improves cycling time trial performance . Int J Sport Nutr Exerc Metab. (2006)
  3. Cheuvront SN, et al No effect of nutritional adenosine receptor antagonists on exercise performance in the heat . Am J Physiol Regul Integr Comp Physiol. (2009)
  4. Talirevic E, Jelena S Quercetin in the treatment of dyslipidemia . Med Arh. (2012)
  5. Kuennen M, et al Thermotolerance and heat acclimation may share a common mechanism in humans . Am J Physiol Regul Integr Comp Physiol. (2011)
  6. Knab AM, et al Quercetin with vitamin C and niacin does not affect body mass or composition . Appl Physiol Nutr Metab. (2011)
  7. Knab AM, et al Influence of quercetin supplementation on disease risk factors in community-dwelling adults . J Am Diet Assoc. (2011)
  8. Boots AW, et al Quercetin reduces markers of oxidative stress and inflammation in sarcoidosis . Clin Nutr. (2011)
  9. Egert S, Rimbach G, Müller MJ No evidence for a thermic effect of the dietary flavonol quercetin: a pilot study in healthy normal-weight women . Eur J Appl Physiol. (2011)
  10. Bigelman KA, et al Effects of 6 weeks of quercetin supplementation on energy, fatigue, and sleep in ROTC cadets . Mil Med. (2011)
  11. Konrad M, et al The acute effect of ingesting a quercetin-based supplement on exercise-induced inflammation and immune changes in runners . Int J Sport Nutr Exerc Metab. (2011)
  12. Abbey EL, Rankin JW Effect of quercetin supplementation on repeated-sprint performance, xanthine oxidase activity, and inflammation . Int J Sport Nutr Exerc Metab. (2011)

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