VO2 Max

VO2 Max refers to the maximal oxygen consumption during exercise, and is thought to reflect the abilities of the cardiorespiratory system (heart and lungs) to handle high intensity cardiovascular exercise (anaerobic exercise).


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This page on VO2 Max is currently marked as in-progress. We are still compiling research.

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The Human Effect Matrix looks at human studies (excluding animal/petri-dish studies) to tell you what what supplements affect VO2 Max
GradeLevel of Evidence
ARobust research conducted with repeated double blind clinical trials
BMultiple studies where at least two are double-blind and placebo controlled
CSingle double blind study or multiple cohort studies
DUncontrolled or observational studies only
Level of Evidence
Magnitude of Effect Size
Scientific ConsensusComments
Comparative Health Goals evidence only available to buyers of our Supplement-Goals Reference

All information is still available and viewable on their respective supplement page.
BFish Oil
BSodium Bicarbonate
CCoenzyme Q10
CVitamin C
CRhodiola Rosea
CGreen Tea Catechins
DEleutherococcus senticosus


  1. Vukovich MD, Stubbs NB, Bohlken RM. Body composition in 70-year-old adults responds to dietary beta-hydroxy-beta-methylbutyrate similarly to that of young adults. J Nutr. (2001)
  2. Thomson JS, Watson PE, Rowlands DS. Effects of nine weeks of beta-hydroxy-beta- methylbutyrate supplementation on strength and body composition in resistance trained men. J Strength Cond Res. (2009)
  3. Nunan D, Howatson G, van Someren KA. Exercise-induced muscle damage is not attenuated by beta-hydroxy-beta-methylbutyrate and alpha-ketoisocaproic acid supplementation. J Strength Cond Res. (2010)
  4. Slater G, et al. Beta-hydroxy-beta-methylbutyrate (HMB) supplementation does not affect changes in strength or body composition during resistance training in trained men. Int J Sport Nutr Exerc Metab. (2001)
  5. Wilson JM, et al. β-Hydroxy-β-methylbutyrate free acid reduces markers of exercise-induced muscle damage and improves recovery in resistance-trained men. Br J Nutr. (2013)
  6. Hoffman JR, et al. Effects of beta-hydroxy beta-methylbutyrate on power performance and indices of muscle damage and stress during high-intensity training. J Strength Cond Res. (2004)
  7. Portal S, et al. The effect of HMB supplementation on body composition, fitness, hormonal and inflammatory mediators in elite adolescent volleyball players: a prospective randomized, double-blind, placebo-controlled study. Eur J Appl Physiol. (2011)
  8. Kreider RB, et al. Effects of calcium beta-hydroxy-beta-methylbutyrate (HMB) supplementation during resistance-training on markers of catabolism, body composition and strength. Int J Sports Med. (1999)
  9. Gallagher PM, et al. Beta-hydroxy-beta-methylbutyrate ingestion, Part I: effects on strength and fat free mass. Med Sci Sports Exerc. (2000)

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